Table I.
miRNA expression by the studied groups.
| Comparison | miRNA | Fold-change | P-value |
|---|---|---|---|
| Tumors vs. healthy tissue | |||
| Upregulation | let-7f-5p | 1.54 | 0.015a |
| miR-30b-5p | 1.49 | 0.039 | |
| let-7e-5p | 1.27 | 0.040 | |
| miR-26a-5p | 1.51 | 0.086 | |
| Downregulation | miR-185-5p | 0.78 | 0.060 |
| Aggressive tumors vs. non-aggressive tumors | |||
| Upregulation | let-7c | 1.85 | 0.005a |
| miR-130a-3p | 1.39 | 0.008 | |
| miR-361-5p | 1.47 | 0.021 | |
| let-7d-5p | 1.45 | 0.022 | |
| miR-99a-5p | 1.67 | 0.025 | |
| miR-29c-3p | 2.29 | 0.043 | |
| let-7f-5p | 1.49 | 0.051 | |
| Downregulation | miR-181a-5p | 0.46 | 0.069 |
| let-7i-5p | 0.67 | 0.075 | |
| Normal tissue adjacent to aggressive vs. non-aggressive tumors | |||
| Upregulation | miR-107 | 1.86 | 0.010a |
| let-7f-5p | 1.72 | 0.016 | |
| miR-30b-5p | 1.40 | 0.062 | |
| Downregulation | miR-34a-5p | 0.67 | 0.015 |
a
False-discovery rate-adjusted P<0.05. miR/miRNA, microRNA.