FIGURE 3.

A representative ESD case treated with O-type HybridKnife. A superficial IIc + IIa type lesion located at the incisura angularis of stomach (A), surface and vascular changes and demarcation line could be visualized clearly by narrow band imaging (NBI) (B). After marking, circumferential cutting was made using the HybridKnife (C). The submucosa was dissected with a satisfactory fluid cushion (D), leaving a clean mucosal defect with supplying vessels close to muscularis propria intact (E). Histological analysis of resected specimen revealed a moderately differentiated intramucosal adenocarcinoma with clean lateral and vertical margins (F).