Figure 2.

PRDX2 knockdown augmented H₂O₂-induced cell death in SMMC-7721 cells. SMMC-7721 cells were transfected with PRDX2 siRNA or non-targeting control siRNA; 48 h later, cells were treated with or without 300 µM H₂O₂ for 24 h. Cell death assays was performed with Annexin V-FITC/PI staining. (A) Representative data. (B) Statistical data. *P<0.05. PRDX2, peroxiredoxin 2; siRNA, small interfering RNA.