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PRDX2 knockdown augmented TNF-α-induced apoptosis in SMMC-7721 cells. SMMC-7721 cells were transfected with PRDX2 siRNA or non-targeting control siRNA; 48 h later, cells were treated with or without 10 ng/ml TNF-α plus 1 µg/ml CHX for 24 h. Cell death assays was performed with Annexin V-FITC/PI staining. (A) Representative and (B) statistical data.*P<0.05. PRDX2, peroxiredoxin 2; siRNA, small interfering RNA; CHX, cycloheximide.
