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Comparison of the GI50 concentrations of anticancer agents against MDA-MB-231 and MDA-MB-231-JYJ cells.
| GI50 (µM) | ||
|---|---|---|
| Compounds | MDA-MB-231 | MDA-MB-231-JYJ |
| SN-38 | 0.034 | 0.018 |
| 5-FU | 2.202 | 2.339 |
| Docetaxel | 0.003 | 0.003 |
| Paclitaxel | 0.008 | 0.021 |
| Dasatinib | 0.014 | N/C |
| Doxorubicin | 0.447 | 0.103 |
GI50, growth inhibition of 50%; 5-FU, 5-fluorouracil; N/C, not calculatable (because MDA-MB-231-JYJ cells did not die much even at higher concentrations than 10 µM of dasatinib).
