miR-103 promoted the proliferation, invasion and migration of colorectal cancer cells by targeting LATS2. (A) SW620 and (B) LoVo cells were cotransfected with miR-103 and pcDNA3.1-LATS2 or a blank vector. A cell counting kit-8 assay was used to measure proliferation. (C) In vitro invasion assay of SW620 and LoVo cells cotransfected with miR-103 and pcDNA3.1-LATS2 or the blank vector. (D) In vitro migration assay of SW620 and LoVo cells cotransfected with miR-103 and pcDNA3.1-LATS2 or the blank vector. Data were drawn from three independent experiments. *P<0.05 vs. miR-103 group. miR, microRNA; NC, negative control; OD, optical density; LATS2, large tumor suppressor kinase 2.