TABLE 2.

Serum cytokine levels in dogs with AF

Cardiac-Derived Production	Sinus Rhythm Control (n = 5)	Sustained AF + Vehicle Infusion (n = 5)	Sustained AF + CI-994–Treated (n = 5)
TNF (pg/h)	3.2 ± 0.9*	64 ± 21†‡	3.5 ± 1.1*
IL-1β (pg/h)	0.1 ± 0.1	0.2 ± 0.1	0.2 ± 0.1
IL-6 (pg/h)	0.5 ± 0.2*,†	52 ± 18†,‡	2.4 ± 1.2*,‡
IL-8 (pg/h)	0.3 ± 0.1*,†	28 ± 10†,‡	1.9 ± 1.0*,‡
IL-10 (pg/h)	0.2 ± 0.2*,†	3.3 ± 0.9‡	2.9 ± 0.7*,‡
Ang-II (ng/h)	0.1 ± 0.1*,†	0.3 ± 0.1†,‡	0.5 ± 0.1*,‡
Resistin (ng/h)	0.1 ± 0.1	0.2 ± 0.1	0.3 ± 0.2
Adipoq. (μg/h)	0.3 ± 0.1*,†	2.1 ± 0.9‡	2.0 ± 1.1‡
Leptin (ng/h)	0.1 ± 0.1	0.3 ± 0.2	0.2 ± 0.1

Adipoq., adiponectin; Ang, angiotensin.

^*P < 0.05 versus AF;

^†P < 0.05 versus CI-994;

^‡P < 0.05 versus control.