Table 2.

SARs of N-linked aryl benzoxazoles. Mean EC₅₀ values ± S.D. and number of replicates (n) for aryl amides with the N-linked aryl benzoxazole scaffold.

	R1	R2	R3	EC50 (μM)	n
28		H	H	1.18 ± 0.01	2
29		H	H	0.31 ± 0.00	2
30		H	Me	0.073 ± 0.019	2
31		OMe	H	0.32 ± 0.11	2
32		Cl	H	0.64 ± 0.24	2
33		H	H	>10	2
34		H	H	> 10	1
35		H	H	0.36	1
36		H	H	0.74 ± 0.04	2
37		H	H	0.17 ± 0.01	2