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. 2016 Apr 8;95(14):e3272. doi: 10.1097/MD.0000000000003272

FIGURE 3.

FIGURE 3

Nesidioblastosis with increased numbers enlarged of Langerhans islets (A–D): (A) H&E; (B) insulin; (C) glucagon; (D) SRIF (somatotropin release-inhibiting factor). (A) Increased number of enlarged Langerhans islets (H&E). (B) The islets consist of mainly of ß-cells (60–70%) which are labeled with antibodies directed against insulin. (C) Approximately 10% to 15% of the islet cells are decorated by antibodies against glucagon and (D) some islet cells are positive with antibodies against somatostatin. Scale bars indicate 100 μm.