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Tdt mononucleotide insertion bias. Mononucleotide frequencies of inserted junctional nucleotides at the V–D and D–J junctions of unique CDR3 nucleotide clonotypes (A) and the overall TCR-β repertoires (B) observed in 10 healthy individuals. CDR = complementarity-determining region, TCR = T cell receptors, Tdt = terminal deoxynucleotidyl transferase.
