Table 3. Estimated treatment effects on patient and carer and outcome measures at all three post-randomisation time points^a.

	Discharge				6 months after discharge				12 months after discharge
	Estimated group differenceb	Test	95% confidence intervalb	Standardised coefficientb	Estimated group differenceb	Test	95% confidence intervalb	Standardised coefficientb	Estimated group differenceb	Test	95% confidence intervalb	Standardised coefficientb
Patient data
BMI (kg/m2) (P)	−0.05	Z=−0.18, P=0.86	−0.57, 0.48	−0.02	−0.07	Z=−0.18, P=0.86	−0.82, 0.69	−0.03	−0.30	Z=−0.71, P=0.48	−1.11, 0.52	−0.14
WHO – Quality of Life Questionnaire (P)	0.13	Z=0.35, P=0.73	−0.62, 0.89	0.05	0.91	Z=2.05, P=0.04	0.04, 1.78	0.38	0.23	Z=0.40, P=0.69	−0.90, 1.37	0.10
Eating Disorder Examination (P)	−0.12	Z=−0.59, P=0.56	−0.54, 0.29	−0.10	−0.47	Z=−2.09, P=0.04	−0.92, −0.03	−0.38	−0.40	Z=−1.46, P=0.15	−0.93, 0.14	−0.32
Depression, Anxiety and Stress Scale (P)	−2.74	Z=−0.68, P=0.50	−10.60, 5.13	−0.10	−4.45	Z=−1.03, P=0.31	−12.97, 4.06	−0.16	−1.58	Z=−0.32, P=0.75	−11.30, 8.13	−0.06
Carer data
Depression, Anxiety and Stress Scale (C)	−0.54	Z=−0.18, P=0.86	−7.29, 6.21c	−0.02	−4.51	Z=−1.40, P=0.16	−11.74, 2.72c	−0.17	−3.24	Z=−0.97, P=0.33	−10.76, 4.28c	−0.12
Family Questionnaire (C)	−1.23	Z=−1.08, P=0.28	−3.45, 1.00	−0.14	−2.24	Z=−2.01, P=0.05	−4.43, −0.05	−0.25	−0.61	Z=−0.45, P=0.66	−3.31, 2.08	−0.07
Accommodating and Enabling Scale for eating disorder (C)	−1.44	Z=−0.51, P=0.61	−7.00, 4.11	−0.06	−3.63	Z=−1.00, P=0.32	−10.77, 3.51	−0.15	−0.22	Z=−0.06, P=0.95	−7.59, 7.14	−0.01
Eating Disorder Symptom Impact Scale (C)	−3.98	Z=−2.05, P=0.04	−7.80, −0.16	−0.29	−3.42	Z=−2.11, P=0.11	−7.56, 0.73	−0.25	−2.16	Z=−0.83, P=0.41	−7.25, 2.93	−0.16
Time spent caregiving (hours/month) (C)	1.02d	Z=0.11, P=0.91	0.68, 1.52d	0.01	0.63d	Z=−1.98, P=0.05	0.40, 1.00d	−0.34	1.04d	Z=0.15, P=0.88	0.58, 1.90d	0.03
WHO – Quality of Life Questionnaire (C)	0.32	Z=1.20, P=0.23	−0.20, 0.84	0.14	0.12	Z=0.41, P=0.77	−0.69, 0.94	0.05	0.40	Z=0.62, P=0.54	−0.88, 1.69	0.17

BMI, body mass index; WHO, World Health Organization; P, patient reported; C, carer reported; TAU, treatment as usual.

^aTime points refer to time since discharge.

^bCoefficients represent estimated treatment effect of ECHO – TAU.

^c97.5% confidence interval (for joint primary outcome).

^dGroup effects represent factor change.

Note: Coach effects were found to be negligible and were therefore not included in the models.