Table 2. Hazard ratio (95% confidence intervals) of incident stroke according to baseline depression status and numbers of depression symptoms.
Variables | No. of subjects | PYs of follow-up | Incident strokes | Incidence rate (per 1000 PYs) | Model 1 | Model 2 |
---|---|---|---|---|---|---|
MDE | ||||||
No | 484 389 | 3 407 861 | 27 440 | 8.05 | 1.00 | 1.00 |
Yes | 2988 | 21 947 | 183 | 8.34 | 1.14 (0.98-1.31) | 1.15 (0.99-1.33) |
No. of depression symptoms | ||||||
0-2 | 484 389 | 3 407 861 | 27 440 | 8.05 | 1.00 | 1.00 |
3 | 475 | 3471 | 25 | 7.20 | 0.92 (0.62-1.36) | 0.99 (0.67-1.47) |
4 | 603 | 4424 | 32 | 7.23 | 0.97 (0.69-1.38) | 1.01 (0.71-1.43) |
5 | 741 | 5490 | 41 | 7.47 | 1.01 (0.75-1.37) | 1.01 (0.74-1.37) |
6 | 719 | 5251 | 53 | 10.09 | 1.37 (1.05-1.79) | 1.33 (1.01-1.74) |
7 | 450 | 3311 | 32 | 9.66 | 1.47 (1.04-2.08) | 1.47 (1.04-2.08) |
P for trend | 0.010 | 0.011 |
Model 1: Adjusted for age and sex.
Model 2: Model 1 plus adjustment for marital status, household income, education, region, smoking status, alcohol consumption, physical activity, BMI, history of hypertension and history of diabetes.
MDE indicates major depressive episodes; and PYs indicates person-years.