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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Stroke. 2016 Jul 28;47(9):2203–2208. doi: 10.1161/STROKEAHA.116.013512

Table 2. Hazard ratio (95% confidence intervals) of incident stroke according to baseline depression status and numbers of depression symptoms.

Variables No. of subjects PYs of follow-up Incident strokes Incidence rate (per 1000 PYs) Model 1 Model 2
MDE
         No 484 389 3 407 861 27 440 8.05 1.00 1.00
         Yes 2988 21 947 183 8.34 1.14 (0.98-1.31) 1.15 (0.99-1.33)
No. of depression symptoms
         0-2 484 389 3 407 861 27 440 8.05 1.00 1.00
          3 475 3471 25 7.20 0.92 (0.62-1.36) 0.99 (0.67-1.47)
          4 603 4424 32 7.23 0.97 (0.69-1.38) 1.01 (0.71-1.43)
          5 741 5490 41 7.47 1.01 (0.75-1.37) 1.01 (0.74-1.37)
          6 719 5251 53 10.09 1.37 (1.05-1.79) 1.33 (1.01-1.74)
          7 450 3311 32 9.66 1.47 (1.04-2.08) 1.47 (1.04-2.08)
P for trend 0.010 0.011

Model 1: Adjusted for age and sex.

Model 2: Model 1 plus adjustment for marital status, household income, education, region, smoking status, alcohol consumption, physical activity, BMI, history of hypertension and history of diabetes.

MDE indicates major depressive episodes; and PYs indicates person-years.