Table 1.

Summary of relative IHC staining signals for eIF4A, eIF4E, and eIF4G in normal sciatic nerves, MPNSTs, and vestibular schwannomas. Tissue sections were processed by immunohistochemistry analysis as described in Materials and Methods. Quantification of immunostaining signal was performed by visual analysis on a 0 to 3+ scale (0 as negative, 0.5+ as weak positive, 1+ as moderate positive, 2+ as strong positive, and 3+ as very strong positive) based on the intensity and percentage of immunopositive cells and their subcellular compartmentalization

Tissue/Tumor	ID No.	eIF4A	eIF4E	eIF4G
Sciatic nerve	1	0 (rare 0.5+)	0	0
	2	0 (occasional 0.5+)	0	0
MPNST	M1	1 ∼ 2 +	2 +	3 +
	M2	0 ∼ 0.5 +	0 ∼ 1 +	0 ∼ 1 +
	M3	1 ∼ 2 +	2 ∼ 3 +	0 ∼ 1 +
	M4	Rare 1+ (mostly necrosis)	0 (necrotic tissue)	0 (necrotic tissue)
	M5	1 +	2 ∼ 3 +	1 ∼ 2 +
	M6	0 ∼ 0.5 +	1 +	3 +
	M7	0.5 ∼ 1 +	1 +	0 ∼ 1 +
	M8	0 (occasional 0.5+)	0	0
	M9	0 with patchy 1 +	0.5 ∼ 1 +	1 ∼ 3 +
	M10	1+ with patchy 2 +	1 ∼ 2 +	3 +
	M11	1 ∼ 2 +	0	0 ∼ 0.5 +
	M12	0 ∼ 1 +	0 ∼ 1 +	1 ∼ 2 +
	M13	1 ∼ 3 +	1 +	3 +
	M14	0 ∼ 0.5 +	1 +	3 +
	M15	1 ∼ 2 +	3 +	1 +
	M16	1 ∼ 2 +	3+ with patchy 2 +	3 +
	M17	0.5 ∼ 1 +	1+ with patchy 2 +	Patchy 3 +
	M18	0 ∼ 0.5 +	0.5 ∼ 1 +	1+ with patchy 2 +
	M19	0 ∼ 0.5 +	1 ∼ 1.5 +	0 ∼ 0.5 +
Vestibular schwannoma	VS1	0 with patchy 2 +	0 ∼ 1 +	1 +
	VS2	2 +	2 ∼ 3 +	1 ∼ 2 +
	VS3	2 ∼ 3 +	2+ with patchy 3 +	1 +
	VS4	2 ∼ 3 +	1+ with patchy 2 +	1 +
	VS5	1 +	1 +	1 +
	VS6	1 ∼ 2 +	3 +	ND
	VS7	2 ∼ 3 +	3 +	1 ∼ 2 +
	VS8	1 +	3 +	1+ with patchy 2 +
	VS9	1 +	0.5 ∼ 1+	2 +
	VS10	3 +	3 +	1 ∼ 1.5 +
	VS11	3 +	3 +	1 ∼ 2 +
	VS12	3 +	3 +	0.5 ∼ 1 +
	VS13	1+ with patchy 3 +	3 +	0.5 ∼ 1 +
	VS14	1 ∼ 2 +	1 +	1 +
	VS15	2 ∼ 3 +	3 +	2 +
	VS16	1 ∼ 2 +	2 ∼ 3 +	2 +
	VS17	3 +	1 ∼ 2 +	1 +
	VS18	2 ∼ 3 +	1 +	0 with patchy 2 +
	VS19	2 ∼ 3 +	2+ with patchy 3 +	0 with patchy 1 +
	VS20	2 ∼ 3 +	1 ∼ 2 +	ND