Chart 3.
Atopic dermatits and innate immune system |
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• Changes in pathogen recognition receptors |
• Defects in Toll-like receptor 2 contribute to increased |
colonization and infection by S. aureus |
• Anti-mycobians peptides (AMPs) |
• Main AMPs: catelicidin (LL37) and β-defensin |
• Decreased AD expression. Favors skin infections |