Table 1. The type and amount of fluids given in each group.
Group | Type of fluids | Amount of fluids |
---|---|---|
sham | No fluids | No fluids |
S | No fluids | No fluids |
LR | LR (30ml/h × 6h) | LR:180ml |
MT | melatonin (50mg/kg) + LR (30ml/h × 6h) | melatonin:11.71 ± 0.12 mg; LR:180ml |
HS | hypertonic saline (6ml/kg) + LR (30ml/h × 6h) | hypertonic saline:1.41± 0.02 ml; LR:180ml |
HES | hydroxyethyl starch (30ml/kg) + LR (30ml/h × 6h) | hydroxyethyl starch:7.03 ± 0.06 ml; LR:180ml |
The rats were randomly divided into 6 groups. In the sham group and the Shock group (S group, n = 8), rats were given no fluids. Animals subjected to resuscitation were treated with lactated Ringer solution (LR group,30 mL/h × 6hr), melatonin plus LR (MT group, 50mg/kg), 7.5% hypertonic saline plus LR (HS group, 6ml/kg), or hydroxyethyl starch 130/0.4 plus LR(HES group, 30ml/kg). Data of the amount of fluids are presented as means ± S.E.M., n = 8 in each group.