Table 1. Patient demographics and clinical variables.
| Mild | Moderately severe | Severe | p-value | |
|---|---|---|---|---|
| (n = 128) | (n = 25) | (n = 23) | ||
| Age | 51 (22–86) | 54 (38–91) | 48 (26–82) | ns |
| Gender male (%) | 90 (70.3) | 17 (68) | 15 (65.2) | |
| Comorbidities | ||||
| Cardiovascular (%) | 48 (37.5) | 13 (52) | 6 (26.1) | |
| Chronic lung (%) | 15 (11.7) | 2 (8) | 2 (8.7) | |
| Renal (%) | 3 (2.3) | 2 (8) | 0 (0) | |
| Aetiology | ||||
| Alcohol (%) | 80 (62.5) | 14 (56) | 17 (74) | |
| Gallstone (%) | 24 (18.8) | 9 (36) | 4 (17) | |
| Other/unknown (%) | 24 (18.8) | 2 (8) | 2 (9) | |
| APACHE II | 5 [3–7] | 6 [5–9] | 11 [6–18] | <0.001 |
| SOFA | N/A | N/A | ||
| ICU admission (n) | 0 | 0 | 23 | |
| Days of hospitalization | 4 [3–6] | 10 [6–13] | 15 [12–27] | |
| Hospital mortality | 0 | 0 | 2 | |
| Organ failure | ||||
| Circulatory (%) | 0 (0) | 2 (8) | 12 (52) | |
| Respiratory (%) | 0 (0) | 8 (32) | 20 (87) | |
| Renal (%) | 0 (0) | 0 (0) | 15 (65) | |
| Mechanical ventilation | 0 | 0 | 10 | |
| RRT | 0 | 0 | 7 | |
| Sepsis | 0 | 0 | 0 | |
| CRP (mg/l) | 39 [10–115] | 36 [14–221] | 75 [20–189] | ns |
| Creatinine (μmol/l) | 62 [54–79] | 65 [49–89] | 70 [52–107] | ns |
| Amylase (IU/l) | 295 [135–722] | 460 [186–1079] | 481 [163–1162] | ns |
Severity of pancreatitis classified by the revised Atlanta classification system. Age in years expressed as mean (range). Categorical variables are expressed as numbers. Continuous variables are expressed as median and interquartile range [IQR]. APACHE; Acute physiology and Chronic Health Evaluation Score. SOFA; Sepsis-related Organ Failure Assessment. RRT; renal replacement therapy. CRP; C-reactive protein. Creatinine; plasma concentration of creatinine. Amylase; plasma concentration of amylase. P denotes statistical significance at the level of 0.05.