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. 2016 Aug 25;11(8):e0161304. doi: 10.1371/journal.pone.0161304

Table 3. Odds ratios for individual components of metabolic syndrome according to baseline AST-to-ALT ratio.

Q1 Q2 Q3 Q4 p-value
All subjects N = 576 N = 562 N = 630 N = 508
Large waist circumference Incidence 225 (39.06%) 163 (29%) 150 (23.81%) 89 (17.52%) <0.0001
Odds ratio 1 0.637 (0.498–0.816) 0.487 (0.38–0.625) 0.331 (0.25–0.44) <0.0001
 High triglycerides Incidence 160 (27.78%) 136 (24.2%) 116 (18.41%) 75 (14.76%) <0.0001
Odds ratio 1 0.83 (0.636–1.082) 0.587 (0.447–0.77) 0.45 (0.332–0.611) <0.0001
 Low HDL cholesterol Incidence 280 (48.61%) 270 (48.04%) 294 (46.67%) 232 (45.67%) 0.7615
Odds ratio 1 0.977 (0.775–1.233) 0.925 (0.738–1.16) 0.889 (0.7–1.129) 0.7619
 High blood pressure Incidence 203 (35.24%) 193 (34.34%) 174 (27.62%) 156 (30.71%) 0.0173
Odds ratio 1 0.961 (0.753–1.227) 0.701 (0.549–0.895) 0.814 (0.631–1.05) 0.0176
 High glucose Incidence 126 (21.88%) 93 (16.55%) 94 (14.92%) 75 (14.76%) 0.0037
Odds ratio 1 0.708 (0.526–0.953) 0.626 (0.466–0.841) 0.618 (0.451–0.847) 0.0039
Excluding heavy drinkers N = 527 N = 528 N = 578 N = 466
Large waist circumference Incidence 209 (39.66%) 156 (29.55%) 136 (23.53%) 82 (17.6%) <0.0001
Odds ratio 1 0.638 (0.494–0.824) 0.468 (0.361–0.607) 0.325 (0.242–0.437) <0.0001
 High triglycerides Incidence 138 (26.19%) 123 (23.3%) 105 (18.17%) 64 (13.73%) <0.0001
Odds ratio 1 0.856 (0.647–1.133) 0.626 (0.47–0.834) 0.449 (0.323–0.623) <0.0001
 Low HDL cholesterol Incidence 264 (50.09%) 263 (49.81%) 279 (48.27%) 223 (47.85%) 0.8592
Odds ratio 1 0.989 (0.777–1.259) 0.93 (0.734–1.177) 0.914 (0.712–1.173) 0.8593
 High blood pressure Incidence 182 (34.54%) 177 (33.52%) 158 (27.34%) 144 (30.9%) 0.0465
Odds ratio 1 0.956 (0.741–1.233) 0.713 (0.552–0.921) 0.848 (0.65–1.106) 0.0471
 High blood glucose Incidence 112 (21.25%) 79 (14.96%) 80 (13.84%) 65 (13.95%) 0.0021
Odds ratio 1 0.652 (0.475–0.895) 0.595 (0.434–0.816) 0.601 (0.43–0.84) 0.0023

Data are OR (95% CI) or frequency (%). P values show the trend. A P value <0.05 was considered statistically significant.