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| Year on TDF | Person-years of observation | Number of S-Cr assessments | Crude rate (per person-year) | 95% CI |
|---|---|---|---|---|
| 1st | 3,041.02 | 6,260 | 2.06 | (2.01, 2.11) |
| 2nd | 1,270.4 | 2,236 | 1.76 | (1.69, 1.83) |
| 3rd | 824.6 | 1,445 | 1.75 | (1.66, 1.85) |
| 4th | 515.41 | 781 | 1.52 | (1.41, 1.63) |
| 5th | 220.93 | 361 | 1.63 | (1.47, 1.81) |
| 6th-10th | 121.81 | 228 | 1.87 | (1.64, 2.13) |
TDF, tenofovir disoproxil fumarate; S-Cr, serum creatinine; CI, confidential interval.
