Skip to main content
. Author manuscript; available in PMC: 2017 Aug 22.
Published in final edited form as: Dev Cell. 2016 Aug 22;38(4):399–412. doi: 10.1016/j.devcel.2016.07.023

Figure 5. Mitotic switch ensures rapid activation of Cdk1 during mitosis but does not regulate S-phase Cdk1 activation rate.

Figure 5

(A) Emission ratio of Cdk1 sensor for wildtype embryos (black line) and twine-3A wee1-9A embryos (red line). (B) Average Cdk1 activation rate per cell cycle for wildtype (black) and twine-3A wee1-9A (red) embryos. Error bars, s.e.m., ***, p<0.0001; ns, not significant. (C) Log-log plot of Cdk1 speed versus S-phase Cdk1 activation rate for wildtype (black) and twine-3A wee1-9A (red) embryos. Error bars, 95% CI. Inset, Cdk1 wave speed of wildtype (black) and twine-3A wee1-9A (red) embryos at cycle 13. Error bars, s.e.m. See also Figure S4 and Movie S4.