Table 3. Corrected Associations between PA and Allergic Phenotype.
Models corrected for age, height, season of accelerometry, nutritional intervention, parental education and study center.
Trait | Vigorous activity | Moderate activity | Any sport | ||||
---|---|---|---|---|---|---|---|
% change | P | % change | P | Odds ratio | P | ||
Boys | Conditions | ||||||
Asthma1 (N = 53) | -29.14 | 0.0076 | -12.81 | 0.041 | 0.63 | 0.18 | |
Rhinitis, no asthma2 (N = 50) | -6.83 | 0.59 | -13.14 | 0.037 | 1.17 | 0.69 | |
Atopy, no rhinitis or asthma3 (N = 197) | -4.29 | 0.57 | -4.53 | 0.23 | 0.91 | 0.66 | |
Lung-healthy 4 (N = 238) | (reference) | -- | (reference) | -- | (reference) | -- | |
Symptoms (all subjects) | |||||||
Wheezing (N = 33) | -12.3 | 0.36 | -10.48 | 0.14 | 0.53 | 0.093 | |
Nose/eye symptoms (N = 102) | -5.34 | 0.55 | -4.97 | 0.29 | 1.24 | 0.41 | |
Girls | Conditions | ||||||
Asthma (N = 41) | 23.02 | 0.14 | 9.67 | 0.24 | 2.02 | 0.14 | |
Rhinitis, no asthma (N = 40) | -1.26 | 0.93 | -5.64 | 0.44 | 0.77 | 0.49 | |
Atopy, no rhinitis or asthma (N = 166) | -7.54 | 0.33 | -5.96 | 0.16 | 1.46 | 0.11 | |
Lung-healthy (N = 352) | (reference) | -- | (reference) | -- | (reference) | -- | |
Symptoms (all subjects) | |||||||
Wheezing (N = 40) | 16.37 | 0.29 | 12.77 | 0.12 | 1.23 | 0.62 | |
Nose/eye symptoms (N = 93) | -5.32 | 0.57 | -6.83 | 0.18 | 0.90 | 0.70 |
1) Asthma: At age 15 the subject reported at least 2 of the following traits: doctor diagnosis of asthma at any time since age 3, asthma medication in past 12 months, wheezing in past 12 months, as in Jarvis et al (2012)
2) Rhinitis: Current rhinitis or hayfever at age 15, but no asthma or asthma medicine
3) Atopy: No asthma, no rhinitis, but one or more positive RAST (IgE ≥0.35) for aero-allergens (birch, mugwort, ambrosia, grass, rye, dogs, cats, dust mites (Dermatophagoides pteronyssinus) and indoor mold (Cladosporium herbarum)
4) Lung-healthy: No asthma ever; no current rhinitis; no wheezing or nose/eye symptoms in past year; no current drugs for asthma or rhinitis; no RAST over 0.35 or positive bronchodilator response as defined in Miller et al (2005) and Flexeder et al (2015) [38]
Bold text if p≤ 0.10. P-values from generalized linear models treating VPA and MPA as lognormal, sport as binary (any vs. none.)