Table 3. Comparison frequencies of P2X7R and CARD8 SNPs between gout and controls.
| Genes | Gout (n = 242) | Control (n = 280) | P value | |
|---|---|---|---|---|
| P2X7R* | Genotypes | 0.205 | ||
| CC | 180 (74.4) | 198 (70.7) | ||
| CA | 60 (24.8) | 74 (26.4) | ||
| AA | 2 (0.8) | 8 (2.9) | ||
| Alleles | 0.196 | |||
| C | 420 (86.6) | 470 (83.9) | ||
| A | 64 (13.2) | 90 (16.1) | ||
| CARD8* | Genotypes | 0.763 | ||
| AA | 71 (29.3) | 88 (31.4) | ||
| AT | 121 (50.0) | 131 (46.8) | ||
| TT | 50 (20.7) | 61 (21.8) | ||
| Alleles | 0.876 | |||
| A | 263 (54.3) | 307 (54.8) | ||
| T | 221 (45.7) | 253 (45.2) | ||
The statistical analysis was performed using Pearson χ2 test.
*rs3751142(C>A) in P2X7R gene and rs2043211(A>T) in CARD8.