Table 4. Comparison for clinical parameters of P2X7R and CARD8 SNPs in patients with gout.
| Clinical parameters | P2X7R* | P value | CARD8* | P value | ||||
|---|---|---|---|---|---|---|---|---|
| CC | CA | AA | AA | AT | TT | |||
| Age, yr | 55.0 (45.0-63.0) | 56.0 (46.3-62.3) | 63.5 (40.5-54.8) | 0.283 | 56.0 (45.0-61.0) | 55.0 (44.0-64.0) | 56.0 (48.8-63.0) | 0.675 |
| Onset age, yr | 47.0 (37.1-55.0) | 47.5 (38.0-57.0) | 56.5 (47.0-66.0) | 0.574 | 48.0 (38.0-53.0) | 47.0 (36.0-57.0) | 45.5 (39.5-54.6) | 0.911 |
| Disease duration, yr | 7.0 (3.0-11.0) | 6.0 (3.0-10.0) | 7.0 (7.0-7.0) | 0.841 | 7.0 (4.0-11.3) | 7.0 (3.0-10.0) | 5.0 (3.0-10.0) | 0.369 |
| Body mass index, kg/m2 | 25.3 (23.4-26.9) | 24.9 (22.5-27.2) | 21.7 (21.7-21.7) | 0.431 | 25.6 (23.0-27.4) | 25.0 (23.5-27.1) | 24.5 (22.2-26.6) | 0.420 |
| Uric acid, mg/L | 6.4 (5.1-7.6) | 6.3 (5.2-7.7) | 4.8 (3.2-4.0) | 0.411 | 6.5 (5.3-7.9) | 6.4 (5.0-7.5) | 6.2 (5.3-8.0) | 0.690 |
The statistical analysis was performed using Kruskal-Wallis test.
*rs3751142 (C>A) in P2X7R gene and rs2043211(A>T) in CARD8 gene.