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. 2016 Mar 1;37(8):11135–11145. doi: 10.1007/s13277-016-4828-1

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 3 — Visualization of apoptotic cells treated with the tested derivatives and tirapazamine in hypoxia. The percentage of different cell populations identified by Hoechst (part A) and PI/Annexin V (part B) assay. *p < 0.05 (mean + SD for three independent experiments; n = 3), yellow arrows indicate normal cells, and red arrows indicate apoptosis cells (c control, T tirapazamine, compounds 1–4, apo apoptosis, nec necrosis)