Table 3.
Patient characteristics | Attrition | Attrition rate per 100 person-years (95% CI) | Unadjusted hazard ratio (95% CI) |
---|---|---|---|
Sex | |||
Female | 1,344 | 56.3 (53.4–59.4) | 1 |
Male | 2,368 | 98.7 (94.8–102.8) | 1.5 (1.4–1.6) a |
Age (years) | |||
15–24 | 251 | 55.6 (49.2–63) | 1 |
25–34 | 1,348 | 65.7 (62.3–69.3) | 1 (0.9–1.2) |
35–44 | 1,337 | 83.4 (79–87.9) | 1.1 (1.0–1.3) |
≥45 | 776 | 114.1 (106.3–122.4) | 1.5 (1.3–1.7) a |
Marital status | |||
Single | 758 | 97.5 (90.8–104.7) | 1.3 (1.2–1.4) a |
Married | 1,996 | 66.9 (64.1–69.9) | 1 |
Widowed | 616 | 83.6 (77.2–90.5) | 1.1 (1.0–1.2) a |
Divorced/separated | 257 | 109.3 (96.7–123.5) | 1.4 (1.2–1.6) a |
Literate | |||
No | 509 | 103.9 (95.3–113.4) | 1.5 (1.3–1.6) a |
Yes | 3,119 | 73.3 (70.8–75.9) | 1 |
Employed | |||
No | 993 | 75.7 (71.1–80.5) | 1 |
Yes | 2,555 | 77.4 (74.5–80.5) | 1.1 (1–1.1) a |
WHO Stageb | |||
Stage 1 | 698 | 35.1 (32.6–37.8) | 1 |
Stage 2 | 418 | 45.2 (41.1–49.8) | 1.1 (0.9–1.2) |
Stage 3 | 1,885 | 126.2 (120.6–132) | 2.4 (2.2–2.7) a |
Stage 4 | 597 | 165.5 (152.7–179.3) | 3.0 (2.7–3.3) a |
CD4 count (cells/µL)b | |||
<50 | 518 | 113.3 (104–123.5) | 3.4 (2.9–3.9) a |
50–99 | 368 | 77.4 (69.8–85.7) | 2.3 (2–2.8) a |
100–199 | 353 | 50.8 (45.7–56.4) | 1.5 (1.3–1.8) a |
200–349 | 296 | 33.4 (29.8–37.4) | 1.1 (0.9–1.3) |
350–499 | 281 | 28.5 (25.4–32.1) | 1.1 (0.9–1.2) |
>500 | 266 | 24.8 (22–28) | 1 |
BMI (kg/m2)b | |||
<18.5 | 1,117 | 82.2 (77.5–87.2) | 4.1 (2.4–7.1) a |
18.5–25 | 839 | 37.5 (35–40.1) | 2.2 (1.3–3.7) a |
25–30 | 100 | 28.2 (23.2–34.3) | 1.7 (1.0–3.1) |
30–35 | 26 | 33.7 (23–49.5) | 2.1 (1.1–4.0) a |
>35 | 13 | 14.7 (8.5–25.3) | 1 |
Haemoglobin levelb | |||
Normal | 471 | 26 (23.7–28.4) | 1 |
Mild anaemia | 383 | 35 (31.7–38.7) | 1.3 (1.2–1.5) a |
Moderate anaemia | 801 | 62.1 (58–66.6) | 2.2 (2.0–2.5) a |
Severe anaemia | 403 | 144.3 (130.9–159.1) | 4.8 (4.2–5.5) a |
Hepatitis C infectionb | |||
No | 1,737 | 46.8 (44.6–49) | 1 |
Yes | 186 | 52.9 (45.8–61) | 1.1 (1.0–1.3) |
Hepatitis B infectionb | |||
No | 1,764 | 46.8 (44.6–49) | 1 |
Yes | 156 | 52.9 (45.2–61.9) | 1.1 (0.9–1.3) |
p-value<0.05
measured at enrolment; ‡ The final adjusted Cox-model was tried and included the covariates sex, age, WHO Stage, CD4 count, BMI, and haemoglobin levels. The results are not presented here as all covariates variables were found to violate proportionality assumptions.
HIV, human immunodeficiency virus; ART, antiretroviral therapy; HR, hazard ratio; BMI, body mass index; WHO, World Health Organization