Figure 7.

Models for the interaction of the five different representative peptides with DMPC bilayers, illustrating the observed changes in membrane thickness. Most peptides (Mag2, GS, BP100) caused membrane thinning, as seen from a reduction of both the hydrophobic thickness 2 D_C as well as the bilayer-bilayer repeat distance D_R. PGLa induced no change in 2 D_C and D_R, most likely due to its higher propensity to tilt into the membrane. TisB induced an increase of both 2 D_C and D_R, which can be attributed to an adaptation of membrane thickness to the length of the transmembrane peptide dimer.