Table 2. The different components of work of breathing at different PetCO2 levels.
PetCO2 (mmHg) | Wi (J/L) | Wex (J/L) | Wtot (J/L) | Wrs (J/L) | Wel (J/L) | WPEEPi (J/L) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Normal | COPD | Normal | COPD | Normal | COPD | Normal | COPD | Normal | COPD | Normal | COPD | ||||||
40 | 0.42±0.22* | 0.84±0.47 | 0.00±0.00* | 0.03±0.04 | 0.50±0.26 | 0.88±0.47 | 0.11±0.07** | 0.36±0.20 | 0.31±0.15 | 0.50±0.34 | 0 | 0.02±0.05 | |||||
50 | 0.66±0.33 | 0.96±0.34 | 0.00±0.01* | 0.11±0.11 | 0.66±0.34 | 0.94±0.32 | 0.14±0.14* | 0.33±0.16 | 0.51±0.21 | 0.60±0.25 | 0 | 0.13±0.15 | |||||
55 | 0.77±0.40 | 1.09±0.55 | 0.01±0.02* | 0.07±0.09 | 0.78±0.40* | 1.15±0.59 | 0.23±0.21 | 0.37±0.13 | 0.54±0.25 | 0.73±0.51 | 0 | 0.18±0.20 | |||||
60 | 0.89±0.46* | 1.42±0.48 | 0.09±0.15 | 0.07±0.11 | 0.97±0.47 | 1.49±0.55 | 0.32±0.24 | 0.39±0.16 | 0.57±0.28* | 1.02±0.47 | 0 | 0.51±0.27 | |||||
65 | 1.06±0.36 | 1.40±0.46 | 0.06±0.05 | 0.17±0.15 | 1.12±0.40 | 1.51±0.56 | 0.38±0.24 | 0.33±0.15 | 0.69±0.16 | 1.06±0.32 | 0 | 0.54±0.18 | |||||
70 | 1.26±0.45* | 1.65±0.63 | 0.24±0.28 | 0.17±0.21 | 1.50±0.71 | 1.83±0.73 | 0.49±0.45 | 0.49±0.27 | 0.77±0.15* | 1.16±0.40 | 0 | 0.65±0.26 |
*, the P value of both groups was <0.05. **, the P value of both groups was <0.01. Wi, inspiratory work; Wex, expiratory work; Wtot, total work of breathing; Wrs, work to overcome airway resistance; Wel, work to overcome elestance; WPEEPi, work done to overcome intrinsic PEEP.