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editorial
. 2016 Aug;8(8):1922–1934. doi: 10.21037/jtd.2016.07.40

Table 4. Treatment modalities for rare airway tumors.

Tumor Treatment modality
Oncocytoma Surgical resection
Multimodality bronchoscopic resection
Mucus gland adenoma Multimodality bronchoscopic resection
Surgical resection
Adenoid cystic carcinoma (I) Surgical resection
(II) Multimodality bronchoscopic resection
(III) Pneumonectomy if there is extensive bronchial involvement
(IV) Radiotherapy with radical doses of 60 Gy for palliative therapy
Mucoepidermoid carcinoma Multimodality bronchoscopic resection
Surgical resection
Myoepithelial carcinoma Surgical resection
Papilloma Multimodality bronchoscopic resection
Carcinoid tumor (I) Surgical resection if tumor is localized (if metastatic there is little to offer)
(II) Bronchoscopic ablation
Leiomyoma (I) Surgical resection:
      • tracheal sleeve resection
      • segmental tracheal resection (anastomotic failure due to dehiscence and stenosis)
      • carinal resection
      • endoscopic resection
(II) Multimodality bronchoscopic resection
(III) Segmentectomy or lobectomy for tumors located at the lobar bronchus or more distal locations
Schwannoma (I) Surgical resection
(II) Endoscopic excision for more localized tumors and patients with poor pulmonary function
Hamartoma (I) Multimodality bronchoscopic resection
(II) Surgical resection
Hemangioma (I) Multimodality bronchoscopic resection
(II) Selective bronchial artery embolization by interventional radiology
(III) High-dose corticosteroids in children and young adults
Lipoma (I) Multimodality bronchoscopic resection
(II) Surgical resection if there is atypical features
(III) Lobectomy or pneumonectomy if there is parenchymal involvement
Chondroma Endoscopic excision
Glomus tumor (I) Sleeve resection with primary reconstruction of the trachea
(II) Multimodality bronchoscopic resection if tumor is confined to the airway lumen without extension into the wall or urgent situations to maintain airway patency
Granular cell tumor (I) Surgical resection
(II) Multimodality bronchoscopic resection
Endobronchial T-cell lymphoma (I) Systemic chemotherapy: pirarubicin, cyclophosphamide, vincristine, and steroids
(II) Surgical resection (after chemotherapy)
Fibrosarcoma Multimodality bronchoscopic resection
Chondrosarcoma (I) Surgical resection
(II) Adjuvant chemotherapy and/or radiation therapy for extensive tumors
Inflammatory myofibroblastic tumor (I) Surgical resection (segmental tracheal resection)
(II) Multimodality bronchoscopic resection
(III) Wide local excision along with adjuvant radiation therapy
(IV) NSAIDs, steroids and ALK-inhibitors such as crizotinib in localized, unresectable tumors
Solitary extramedullary plasmacytoma (I) Argon plasma coagulation via rigid bronchoscopy for narrow-base tumors
(II) Surgical resection followed by radiotherapy for wide-base tumors