. 2016 Aug 20;7(8):54. doi: 10.3390/genes7080054

Table 2.

Distributions of the retinoic acid receptor-related orphan receptor alpha (RORA) single-nucleotide polymorphisms (SNPs) in T2DM patients and controls.

SNP	Group		Genotype		HWE ^a				Allele
SNP	Group	Number	p	FDR q ^b	p	Freq. %		p	FDR q ^b	OR [95% CI] ^c
rs17270188		AA/AG/GG				A	G
	T2DM	94/195/138	0.869	0.871	0.112	44.8	55.2	0.614	0.658	0.95 [0.78–1.15]
	Control	93/190/125			0.204	46.1	53.9
rs1898413		AA/AG/GG				A	G
	T2DM	14/112/301	0.772	0.793	0.373	16.4	83.6	0.644	0.681	1.06 [0.82–1.38]
	Control	10/107/291			0.965	15.6	84.4
rs11638541		TT/TC/CC				T	C
	T2DM	336/84/7	0.809	0.822	0.512	88.5	11.5	0.541	0.592	1.10 [0.81–1.50]
	Control	327/76/5			0.806	89.5	10.5
rs8033552		AA/AG/GG				A	G
	T2DM	17/117/293	0.801	0.814	0.225	17.7	82.3	0.494	0.521	1.09 [0.85–1.41]
	Control	14/106/288			0.280	16.4	83.6
rs10851685		TT/TA/AA				T	A
	T2DM	26/156/245	0.029	0.038	0.860	24.4	75.6	0.009	0.015	1.36 [1.08–1.72]
	Control	13/130/265			0.540	19.1	80.9
rs8041381		AA/AG/GG				A	G
	T2DM	310/111/6	0.847	0.864	0.262	85.6	14.4	0.745	0.776	1.05 [0.80–1.38]
	Control	299/105/4			0.113	86.2	13.8
rs340002		AA/AG/GG				A	G
	T2DM	51/204/172	0.804	0.818	0.421	35.8	64.2	0.586	0.601	1.06 [0.871–1.29]
	Control	43/196/169			0.210	34.6	65.4
rs340023		CC/CT/TT				C	T
	T2DM	68/189/170	0.661	0.692	0.206	38.1	61.9	0.421	0.479	1.09 [0.89–1.32]
	Control	56/183/169			0.566	36.2	63.8
rs28724570		CC/CT/TT				C	T
	T2DM	107/215/105	0.311	0.358	0.884	50.2	49.8	0.134	0.142	1.16 [0.96–1.40]
	Control	90/200/118			0.762	46.6	53.4

^a HWE: Hardy-Weinberg equilibrium. ^b FDR q: false discovery rate q value. ^c OR: odds ratio; CI: confidence interval. p or q value of 0.05 is in bold.