Table 3.
Association between RORA SNPs and the risk of T2DM under different genetic models.
| SNP | Genetic Model a | p Value | FDR q | OR [95% CI] | |
|---|---|---|---|---|---|
| rs17270181 | Dominant | (AG + AA) vs. GG | 0.183 | 0.231 | 1.32 [0.88–2.01] |
| rs1898413 | Additive | AG vs. GG | 0.918 | 0.921 | 1.01 [0.81–1.26] |
| AA vs. GG | 0.384 | 0.413 | 1.30 [0.72–2.34] | ||
| rs11638541 | Dominant | (AG + GG) vs. AA | 0.222 | 0.298 | 1.15 [0.92–1.44] |
| rs8033552 | Recessive | AA vs. (AG + GG) | 0.178 | 0.202 | 1.34 [0.87–2.05] |
| rs10851685 | Dominant | (TA + TT) vs. AA | 0.025 | 0.032 | 1.38 [1.04–1.82] |
| rs8041381 | Dominant | (AG + GG) vs. AA | 0.333 | 0.402 | 0.88 [0.58–1.33] |
| rs340002 | Dominant | (AG + AA) vs. GG | 0.699 | 0.748 | 1.04 [0.86–1.26] |
| rs340023 | Recessive | CC vs. (CT + TT) | 0.195 | 0.243 | 1.21 [0.91–1.62] |
| rs28724570 | Recessive | CC vs. (CT + TT) | 0.057 | 0.103 | 1.79 [0.98–3.23] |
a For each SNP, only the best genetic model determined by Akaike’s information criterion (AIC) is provided. The ORs and CIs that are statistically significant are bolded, along with the rs number of the corresponding SNP.