Table 4.
Frequencies of pairwise haplotype constructed by SNPs in RORA.
| Haplotype a | Freq. (case) | Freq. | χ2 | Fisher’s p | OR [95% CI] b |
|---|---|---|---|---|---|
| (control) | |||||
| GGTGTAGTT | 0.044 | 0.031 | 1.03 | 0.417 | |
| GGTGTAGTT | 0.072 | 0.056 | 2.37 | 0.097 | |
| GGTGTAACT | 0.102 | 0.058 | 8.38 | 0.004 | 2.11 [1.31–3.42] |
| GGTGTAACC | 0.093 | 0.024 | 17.21 | 5.27 × 10−5 | 3.26[1.78–5.95] |
| GATATAGCT | 0.061 | 0.06 | 3.01 | 0.086 | |
| GATGAGGTT | 0.038 | 0.029 | 0.08 | 0.862 | |
| GATGAAGTT | 0.179 | 0.234 | 13.46 | 0.0001 | 0.54 [0.39–0.81] |
| AGTGAAGTT | 0.033 | 0.054 | 5.36 | 0.018 | 0.49 [0.29–0.91] |
| GATATAACT | 0.046 | 0 | 19.51 | 1.72 × 10−6 | |
| AATGAAATT | 0 | 0.034 | 18.79 | 1.16 × 10−5 |
a The order of SNPs from left to right is rs17270188, rs1898413, rs11638541, rs8033552, rs10851685, rs8041381, rs340002, rs340023 and rs28724570. Only haplotypes with a frequency > 3% in at least one group were listed. b Only haplotypes distributed significantly differently (p < 0.05) were calculated. The OR could not be calculated for the haplotypes GATATAACT and AATGAAATT, because of the zero value in the population.