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. 2016 Jul 28;8(8):232. doi: 10.3390/toxins8080232

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Overview of deacetylation of 3/15ADON in humans. Based on specific activities calculated in Table 3, we were able to assess the respective implication of enzymes, cells and tissues, expressed as percentage of total activity, in the deacetylation of 3- and 15ADON in humans, the contribution of each compartment being calculated considering that total 3/15-ADON deacetylation activity is the sum of specific activities of digestive enzymes, fecal bacteria, small intestinal, hepatic and colonic tissues.