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| Cell type | Type of receptor | Function |
|---|---|---|
| Neuron | S1P1 = S1P3 > S1P2 = S1P5 | Neurogenesis, neural progenitor migration, cell survival, and neurotransmission |
| Oligodendrocyte | S1P5 > S1P1 = S1P2 > S1P3 | Oligodendrocyte precursor cell survival, migration, differentiation, and morphology |
| Astrocyte | S1P3 > S1P1 > S1P2 > S1P5 | Proliferation, migration, gap function communication, and growth factor production |
| Microglia | S1P1 > S1P2 > S1P3 = S1P5 | Pro-inflammatory cytokine production |
