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. 2016 Aug 26;6:30745. doi: 10.1038/srep30745

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Copyright © 2016, The Author(s)

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Blood glucose (a) and insulin (b) levels during the ivGTT. The upper panel of each figure represents the area under the curve (AUC). NL-S, normal litter rats treated with saline solution; SL-S, small litter rats treated with saline solution; NL-B, normal litter rats treated with scopolamine butylbromide; SL-B, small litter rats treated with scopolamine butylbromide. Data are expressed as the mean ± SEM of 9–17 rats from each experimental group. L, litter size factor; T, treatment factor; and I, interaction between litter size and treatment factors. *P < 0.05, **P < 0.01, ****P < 0.0001, based on a two-way analysis of variance. ^ɸɸP < 0.01 and ^ɸɸɸP < 0.001, statistical significance of differences between NL and SL; ^##P < 0.01, ^###P < 0.001 and ^####P < 0.0001, statistical significance of saline versus scopolamine butyl bromide animals, based on the Tukey multiple comparisons test.