Figure 6.
Expression of autophagic proteins (ATG7, ATG10, ATG5, UVRAG, BECN1, and ULK1) in human tumor cells upon exposure to indicated marine drugs. Tested tumor cells were exposed to control medium (−) or medium with chromomycin A2 (+, 30 nM, panel A), psammaplin A (+, 7.5 µM, panel B), or ilimaquinone (+, 10 µM, panel C) for 16 h. Total protein lysates were analyzed by immunoblotting with indicated antibodies against ATG7, ATG10, ATG5, UVRAG, ULK1, and BECN1. Level of β-tubulin served as a loading control.