FIG 2 .

5-Fluorouracil rescues C. elegans from P. aeruginosa-mediated killing. (A) Tiled fluorescence images of a plate from NINDS custom collection 2. A well (O18) containing 5-fluorouracil is circled in orange. Columns 1 and 23 represent gentamicin (positive control; outlined in blue). Columns 2 and 24 represent DMSO (negative control; outlined in red). Columns 3 to 22 represent 320 different small molecules, the majority of which do not alleviate host killing. Library plates were screened in duplicate. Data from a representative replicate of the plate noted are shown. (B) Single-well images of worms exposed to 5-fluorouracil (FU; well O18) showing bright-field results (top) and fluorescence (bottom).