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. 2016 Jul 8;291(35):18525–18535. doi: 10.1074/jbc.M116.738336

FIGURE 6.

FIGURE 6.

Placental Mttp transcriptional regulation and activity upon maternal apo10AL or apo10OL administration. A and B, qPCR analysis of placental Cyp26A1, apoB, Mttp, and transcription factors of Mttp (A) and placental MTP activity (B) of WT dams i.p. injected with vehicle (Veh) (n = 5, i.e. one to two placentas/dam from four dams) or apo10AL (n = 6, i.e. two placentas/dam from three dams) and sacrificed after 24 h. C and D, qPCR analysis of placental Cyp26A1, apoB, Mttp, and transcription factors of Mttp (C) and placental MTP activity (D) of WT dams i.p. injected with vehicle (n = 5, one to two placentas/dam from three dams) or apo10AL (n = 6, i.e. two placentas/dam from three dams) and sacrificed after 4 h. E and F, qPCR analysis of placental Cyp26A1, apoB, Mttp, and transcription factors of Mttp (E) and placental MTP activity (F) of WT dams i.p. injected with vehicle (n = 5, i.e. one to two placentas/dam from four dams) or apo10OL (n = 4, i.e. one to two placentas/dam from three dams) and sacrificed after 24 h. Data are expressed as mean ± S.D. (error bars) of triplicate determinations. Statistical analysis was by Student's t test. *, p < 0.05. apoAL, apo10AL; apoOL, apo10OL.