Fig. 13.

Phamily circles indicate relationships of large terminase proteins. Clusters (A1-F2) were intentionally set to group phages with similar packaging strategies together. a Pham 323 contains only three large terminase proteins, indicated by bolded gp designations. The three phages that encode these terminases belong to cluster E4, which includes phages that use headful packaging (Sf6) [41, 42]. b Pham 2966 contains only three large terminases, indicated by bolded gp designations. The three phages that contain these terminases belong to cluster C3, which includes phages that have short exact DTRs (C-st). These proteins meet the cutoff parameters to be included in pham 2966, but do not meet the parameters required to draw connecting lines (see Fig. 13a). c An overlay of 15 pham circles represents large terminase proteins for every phage in the database. This circle indicates that large terminases grouped into the same pham belong to phages that use the same packaging strategy. In this database, no terminases were grouped with terminases belonging to phages that use a different packaging strategy. Gene products connected by red lines have an E-value of less than 1e-50. Gene products connected by blue lines share more than 32.5 % identity