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. 2016 Aug 26;17(1):679. doi: 10.1186/s12864-016-3018-2

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Neighbor-joining tree of large terminase proteins. This tree was generated by ClustalX [13], displayed in Mega6 [40], and contains large terminase sequences from phages with experimentally determined packaging mechanisms and physical ends (see Additional file 1). Bootstrap values are for 1000 trials. The scale bar shows 0.1 amino acid substitutions per site. We manually assigned clusters in Phamerator that correspond to packaging strategies. For example, phages that use 3’ cos ends (HK97) are assigned to cluster A1. This phylogenetic tree indicates that large terminase proteins sharing phamilies and packaging strategies also clade together