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. 2016 Aug 26;16(1):317. doi: 10.1186/s12906-016-1296-5

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Response surface plot for the effects of extraction temperature, extraction time, solvent-liquid ratio, and solvent volume on total polyphenol content of extract. (X₁, extraction temperature (°C); X₂, extraction time (hour); X₃, Solid-liquid ratio (%); X₄, solvent volume (1:X); Y₂, total polyphenol content (mg GAE/g))