Table 1.
Inhibitory effect of the crude extract and fractions of Zea mays L. on protein tyrosine phosphatase 1β
| Extract and fractions | Concentration (μg/mL) | Inhibition (%) | IC50 b (μg/mL) |
|---|---|---|---|
| Suramina | 12.97 | 61.88 | |
| 6.49 | 40.62 | 7.51 | |
| 3.21 | 10.69 | ||
| EtOH ext. | 100 | 43.99 | - |
| n-Hex fr. | 100 | 25.54 | - |
| CH2Cl2 fr. | 100 | 28.12 | - |
| EtOAc fr. | 100 | 83.88 | |
| 50 | 57.23 | 26.12 | |
| 10 | 44.77 | ||
| n-BuOH fr. | 100 | 70.89 | |
| 50 | 45.09 | 58.20 | |
| 10 | 26.87 | - | |
| Water fr. | 100 | 47.50 | - |
aSuramin was used as positive control
bThe IC50 value was defined as the half-maximal inhibitory concentration and mean of 3 duplicate analyses of each sample