Table 1.
Selected genes involved in adipogenic differentiation
| Gene name | Protein function | Inhibitor | Effect |
|---|---|---|---|
| ADAMTS5 | Metalloproteinase | Batimastat | Positive |
| AGTR1 | Angiotensin II receptor | Losartan | Negative |
| AKR1B10 | Aldo-keto reductase | Zopolrestat | Positive |
| BDKRB2 | Bradykinin receptor B2 | Icatibant | Negative |
| CXCL12 | Chemokine SDF-1 | (Not tested) | (Not tested) |
| KCNK3 | Potassium channel | Doxapram | Negative |
| PPARG | Nuclear receptor | GW9662 | Positive |
| PRKAR2B | cAMP protein kinase | (Not tested) | (Not tested) |
| VCAM1 | Vascular cell adhesion | (Not tested) | (Not tested) |
Table presents the HUGO name, function, commercially available drug, and status of experimentally observed effects
positive observed effect, negative no observed effect