Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 25;13(1):196. doi: 10.1186/s12974-016-0683-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — Telmisartan has no effect on the local CNS inflammatory response induced following NSV infection. At peak inflammation (day 6), total MNC infiltration was not suppressed in either the brains or spinal cords of mice (n = 5 mice per group) treated with telmisartan (100 mg/kg/day) compared to a vehicle control (a). By flow cytometry, the proportions of different brain-infiltrating myeloid cell subsets (CD45+/CD11b+) were not different between these two groups (b). Likewise, expression of CD40 (c) and CD86 (d) were not changed on any resident or CNS-infiltrating myeloid cell subset in the setting of drug treatment as assessed by the mean fluorescence intensity (MFI) of staining for the two activation markers