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. 2016 Aug 25;47(1):87. doi: 10.1186/s13567-016-0372-7

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Pyk is crucial for the virulence of B. abortus in mouse model of infection. A Bacterial loads of the S2308 strain, the pyk mutant in the spleens of BALB/c mouse at 1 and 5 weeks post-infection. B Spleen weight of the S2308 strain and the pyk mutant infected mice at 1 and 5 weeks post-infection. C Bacterial loads of the S2308 strain, the pyk mutant and the complementation strain in the spleens of BALB/c mouse at 1 week post-infection. D Spleen weight of the S2308 strain, the pyk mutant and the complementation strain infected mice at 1 week post-infection *p ≤ 0.05; ***p ≤ 0.001.