Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Aug 25;10(1):84. doi: 10.1186/s12918-016-0303-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 6 — We consider the 5 signaling regimes corresponding to motifs of Fig. 5, as well as associated parameter restrictions characterizing each of them (see details in Discussion). Then, each panel displays the probabilities of a given signaling regime in function of the considered parameter restrictions. Consistently, the probability to get a given signaling regime is maximized by choosing the parameter restrictions characterizing it, and this maximum is significantly higher than the probability obtained from a log-uniform distribution of biochemical parameters without any restriction (cf. first bar of the histogram, NR)