Table 1.
Sufficient conditions to optimize the forward signaling. The second column reports combined parameter ranges able to enhance the forward response for convex (χ≤0) and logistic-like (χ>0) curves, deduced analytically from the criteria of efficient forward signaling. The third column refers to conditions obtained below, with a numerical method based on a random parameter sampling and maximizing the likelihood of these parameters with respect to the forward signaling (See Discussion section)
| Parameters | Suff. conditions for | Maximizing likelihood | |
|---|---|---|---|
| χ≤0 | χ>0 | (cf. discussion below) | |
| >1 | ≪1 | a 3≫1 | |
| <1 | <1 | b i≪1 | |
| ≫1 | ≫1 | 1/e i>1 | |
| ≪1 | ≪1 | c i−e i<1 | |
| >1 | ≪1 | a i/b i>1 | |