Table 4.
Overall drop-out rate and main reasons for treatment discontinuation in the NEONet database
| Patient population (n = 221) | Drop-out patients (70, 32 %) | Patients under treatment (151, 38 %) | p-value |
|---|---|---|---|
| Males, n (%) | 25 (35.71) | 68 (45.03) | 0.0959 |
| Females, n (%) | 45 (64.29) | 83 (54.97) | |
| Age-years, mean (SD) | 46.79 (14.82) | 47.44 (13.11) | 0.4904 |
| Treatment duration-months, mean (SD) | 27.69 (20.94) | 27.54 (22.96) | 0.4992 |
| Reason for drop-out, n (%) | |||
| Lack of efficacy | 18 (26) | ||
| Patient’s decision discontinuation | 34 (49) | ||
| Efficacy | 4 (6) | ||
| Adverse events (local or systemic reactions) | 5 (7) | ||
| Onset of contraindications | 6 (8) | ||
| Patient moved to another referral center | 3 (4) | ||
NEONet North East Omalizumab Network, SD standard deviation