Table 1.
Comparison of clinical characteristics between patients with serum uric acid (SUA) <7 and ≥7 mg/dL.
| Characteristics | All Patients (n = 385) | SUA < 7 mg/dL (n = 292) | SUA ≥ 7 mg/dL (n = 93) |
|---|---|---|---|
| Age (year) | 64.6 ± 12.1 | 63.7 ± 11.6 | 67.3 ± 13.3 * |
| Male gender (%) | 49.6 | 43.5 | 68.8 |
| CAD (%) | 6.6 | 7.2 | 4.3 |
| CVD (%) | 3.8 | 2.7 | 7.2 |
| Duration of DM (years) | 9 (5–16) | 9 (4–15) | 11 (6–16) |
| Systolic BP (mmHg) | 138.6 ± 17.8 | 137.3 ± 17.1 | 142.7 ± 19.6 * |
| Diastolic BP (mmHg) | 76.1 ± 11.9 | 76.0 ± 11.5 | 76.1 ± 13.0 |
| WC (cm) | 92.6 ± 11.1 | 91.0 ± 10.4 | 97.5 ± 11.7 ** |
| HC (cm) | 100.0 ± 10.0 | 99.3 ± 10.2 | 102.4 ± 9.4 |
| W-to-H ratio | 0.93 ± 0.07 | 0.92 ± 0.07 | 0.95 ± 0.06 * |
| BMI (kg/m2) | 26.4 ± 4.6 | 26.1 ± 4.4 | 27.3 ± 5.2 |
| Laboratory parameters | |||
| Uric acid (mg/dL) | 5.9 ± 1.8 | 5.1 ± 1.1 | 8.3 ± 1.3 ** |
| Triglyceride (mg/dL) | 121 (83.5–172) | 117 (78–164) | 144 (99.5–206.5) * |
| Total cholesterol (mg/dL) | 180.6 ± 47.7 | 179.9 ± 46.4 | 182.9 ± 51.6 |
| HDL-cholesterol (mg/dL) | 45.0 ± 12.9 | 46.4 ± 13.0 | 40.8 ± 11.6 * |
| LDL-cholesterol (mg/dL) | 101.7 ± 35.4 | 100.8 ± 33.2 | 104.5 ± 41.6 |
| Fasting glucose (mg/dL) | 154.8 ± 64.3 | 158.4 ± 67.3 | 143.4 ± 52.6 * |
| HbA1c (g/dL) | 7.6 ± 1.9 | 7.6 ± 1.9 | 7.5 ± 1.9 |
| eGFR (mL/min/1.73 m2) | 78.6 ± 33.0 | 84.5 ± 31.5 | 60.0 ± 30.7 ** |
| Urinary albumin-to-creatinine ratio (UACR) (mg/gm) (p < 0.001) | |||
| <30 | 60.3 | 66.4 | 40.9 |
| 30–300 | 26.0 | 22.9 | 35.5 |
| ≥300 | 13.8 | 10.6 | 23.7 |
| Diabetic retinopathy (DR) (p = 0.051) | |||
| NDR | 75.8 | 78.1 | 68.9 |
| NPDR | 19.0 | 18.2 | 21.5 |
| PDR | 5.2 | 3.8 | 9.7 |
* p < 0.05, ** p < 0.001 compared to patients with SUA <7 mg/dL. CAD, coronary artery disease; CVD, cerebrovascular disease; DM, type 2 diabetes mellitus; BP, blood pressure; WC, waist circumference; HC, hip circumference; W-to-H, waist-to-hip circumference ratio; BMI, body mass index; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HbA1c, glycated hemoglobin; eGFR, estimated glomerular filtration rate; NDR, no apparent DR; NPDR, non-proliferative DR.