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. 2016 Aug 10;17(8):1284. doi: 10.3390/ijms17081284

Figure 2.

Figure 2

Effect of high cholesterol and WGLL on cardiac function. Hearts were isolated from three groups of animals (n = 6), defined as follows: non-hypercholesterolemic animals fed with normal chow (control); hypercholesterolemic group fed with 2% cholesterol-supplemented chow (HC); and a group of hypercholesterolemic animals treated with WGLL (HCT). Isolated working hearts harvested from each animal in each group were subjected to global ischemia followed by 120 min of reperfusion (I/R). Cardiac functions were registered before ischemia (preischemic) and 60 min after global ischemia (60 min of reperfusion). Results are shown as average values from each group of rabbits ± SEM of aortic flow (AF, mL/min, A); coronary flow (CF, mL/min, B); aortic pressure (AoP, Hgmm, C); heart rate (HR, beat/min, D); cardiac output (CO, mL/min, E); stroke volume (SV, mL, F). * p < 0.05 compared to the preischemic control; ** p < 0.05 compared to the 60 min of reperfusion control; ## p < 0.05 compared to the 60 min of reperfusion HC.