Table 2.
Effects of CML or pentosidine at 0 (control), 1, 2, 4, 8 or 16 μmol/L upon cell invasion (% of control) and migration (% of control) in human A549 and Calu-6 cells. Cells were exposed to CML or pentosidine for 18 h at 37 °C. Data are mean ± SD (n = 10). a–e Means within a column without a common letter differ, p < 0.05.
| A549 Cells | Calu-6 Cells | |||
|---|---|---|---|---|
| Invasion | Migration | Invasion | Migration | |
| CML, 0 | 100 a | 100 a | 100 a | 100 a |
| 1 | 102 ± 3 a | 98 ± 4 a | 99 ± 2 a | 98 ± 5 a |
| 2 | 107 ± 4 a | 106 ± 5 a | 127 ± 4 b | 132 ± 3 b |
| 4 | 135 ± 3 b | 140 ± 7 b | 155 ± 5 c | 158 ± 4 c |
| 8 | 142 ± 5 b | 144 ± 5 b | 182 ± 4 d | 187 ± 6 d |
| 16 | 166 ± 7 c | 174 ± 4 c | 190 ± 6 d | 195 ± 5 d |
| Pentosidine, 0 | 100 a | 100 a | 100 a | 100 a |
| 1 | 99 ± 2 a | 104 ± 5 a | 103 ± 4 a | 107 ± 4 a |
| 2 | 103 ± 5 a | 108 ± 3 a | 133 ± 2 b | 147 ± 3 b |
| 4 | 138 ± 4 b | 142 ± 4 b | 164 ± 5 c | 173 ± 6 c |
| 8 | 157 ± 5 c | 168 ± 6 c | 191 ± 7 d | 205 ± 5 d |
| 16 | 184 ± 7 d | 201 ± 4 d | 225 ± 6 e | 232 ± 3 e |