. 2016 Aug 9;17(8):1289. doi: 10.3390/ijms17081289

Table 3.

Effects of CML or pentosidine at 0 (control), 1, 2, 4, 8 or 16 μmol/L upon ROS (RFU/mg protein), TNF-α (pg/mg protein), IL-6 (pg/mg protein) and TGF-β1 (pg/mg protein) levels in human A549 and Calu-6 cells. Cells were exposed to CML or pentosidine for 18 h at 37 °C. Data are mean ± SD (n = 10). ^a–e Means within a column without a common letter differ, p < 0.05.

	A549 Cells				Calu-6 Cells
	ROS	TNF-α	IL-6	TGF-β1	ROS	TNF-α	IL-6	TGF-β1
CML, 0	1.97 ± 0.18 ^a	156 ± 13 ^a	133 ± 10 ^a	141 ± 8 ^a	2.09 ± 0.21 ^a	160 ± 18 ^a	136 ± 8 ^a	130 ± 7 ^a
1	2.06 ± 0.21 ^a	161 ± 9 ^a	142 ± 8 ^a	147 ± 5 ^a	2.14 ± 0.15 ^a	158 ± 12 ^a	142 ± 14 ^a	139 ± 10 ^a
2	2.18 ± 0.25 ^a	167 ± 17 ^a	150 ± 16 ^a	163 ± 11 ^a	2.23 ± 0.24 ^a	166 ± 9 ^a	148 ± 10 ^a	145 ± 12 ^a
4	2.65 ± 0.17 ^b	194 ± 14 ^b	187 ± 11 ^b	197 ± 9 ^b	2.71 ± 0.17 ^b	201 ± 15 ^b	191 ± 16 ^b	186 ± 8 ^b
8	2.84 ± 0.20 ^b	237 ± 22 ^c	224 ± 19 ^c	245 ± 13 ^c	3.18 ± 0.23 ^c	242 ± 13 ^c	247 ± 19 ^c	217 ± 14 ^c
16	3.39 ± 0.28 ^c	280 ± 19 ^d	275 ± 23 ^d	291 ± 17 ^d	3.30 ± 0.28 ^c	293 ± 20 ^d	258 ± 25 ^c	266 ± 21 ^d
Pentosidine, 0	2.08 ± 0.11 ^a	149 ± 15 ^a	136 ± 7 ^a	139 ± 9 ^a	2.21 ± 0.14 ^a	152 ± 12 ^a	130 ± 11 ^a	134 ± 9 ^a
1	2.13 ± 0.16 ^a	157 ± 12 ^a	145 ± 14 ^a	148 ± 10 ^a	2.18 ± 0.19 ^a	159 ± 8 ^a	127 ± 14 ^a	143 ± 13 ^a
2	2.62 ± 0.09 ^b	188 ± 10 ^b	176 ± 18 ^b	182 ± 13 ^b	2.57 ± 0.12 ^b	195 ± 16 ^b	178 ± 15 ^b	175 ± 15 ^b
4	2.75 ± 0.21 ^b	226 ± 19 ^c	213 ± 15 ^c	234 ± 8 ^c	3.06 ± 0.20 ^c	240 ± 23 ^c	201 ± 19 ^b	223 ± 10 ^c
8	3.55 ± 0.18 ^c	270 ± 22 ^d	259 ± 17 ^d	290 ± 14 ^d	3.59 ± 0.16 ^d	291 ± 26 ^d	263 ± 25 ^c	279 ± 14 ^d
16	3.69 ± 0.25 ^c	331 ± 27 ^e	304 ± 22 ^e	359 ± 19 ^e	3.74 ± 0.25 ^d	355 ± 21 ^e	310 ± 27 ^d	348 ± 16 ^e